Testing FAQs

I am a physician. How do I order testing?

Please visit our test catalog to find the appropriate test. You can search for a test by entering a specific test name, test code, or gene of interest in the search field.  Select your test to learn more, including methodology, sample type, turnaround time for results, CPT code information, and requisition.

 


What sample type(s) do you accept for testing?

Sample types vary by test. Visit our test catalog to find validated sample types and preferred amounts for the test you intend to order. Requisitions also list acceptable specimen types and amounts. If you are considering using an unvalidated sample type or substantially lower amount, please contact us by calling 1.800.411.4363 or by filling out our contact form.

 


 

What is the best specimen type for my patient who recently had a blood transfusion?

Unless the study is being done specifically to monitor for results related to the transfusion, blood is not an acceptable specimen type for these individuals, as results may represent the donor rather than the patient. Saliva and buccal specimens may be considered however studies show these may also represent the donor rather than the patient. For patients with recent blood transfusions, we prefer to receive either a pre-transfusion blood specimen or DNA extracted from a pre-transfusion specimen if available.  Otherwise, wait approximately 72 hours post-transfusion for a repeat blood draw for all molecular studies other than mitochondrial DNA studies. For mitochondrial DNA studies, please wait approximately 6 weeks after the transfusion. If this is not possible, please see the listing of alternate specimen types by searching under the desired test code here on our website.

 


 

What is the best specimen type for my patient who recently had a bone marrow transplant?

Unless the study is being done specifically to monitor for results related to the transplant, blood is not an acceptable specimen type for these individuals as results may represent the bone marrow donor rather than the patient. Saliva and buccal specimens would not be ideal as studies show these can also represent the bone marrow donor rather than the patient. For patients with bone marrow transplants, we prefer to receive either a pre-transplant blood specimen or DNA obtained from a pre-transplant specimen if available. If this is not possible, please see the listing of alternate specimen types by searching under the desired test code here on our website.

 


What is the difference between Baylor Genetics’ various carrier screening (GeneAware) options?

BG offers four carrier screening panel options for males and females to best meet the needs of patients: Basic, ACMG & ACOG, Ashkenazi Jewish, and Complete. The Basic panel includes an assessment of the smallest panel of most frequently ordered disorders. The ACMG & ACOG panels include assessment of those on the Basic panel and additional conditions, as recommended to be offered to all women and couples considering pregnancy or currently pregnant. The Ashkenazi Jewish Panel includes an assessment of disorders on the ACMG&ACOG panel, along with those most commonly observed in the Ashkenazi Jewish population. The Complete panel includes all those on the Ashkenazi Jewish panel, along with many others to provide the most comprehensive screening for family planning decisions. Additional information regarding our GeneAware options can be found, here. 

 


What are Baylor Genetics’ Mitochondrial DNA testing options?

BG offers some of the most comprehensive mtDNA testing available, including NGS analysis of each the mtDNA genome and select nuclear genes associated with mitochondrial disease, numerous mitochondrial NGS panels targeted to various mitochondrial phenotypes and underlying etiology, numerous metabolic panels by phenotype and underlying etiology, and Electron Transport Chain and mtDNA copy number analysis. Further information regarding our various testing options can be found, here 

 


What are your eligibility criteria for Baylor Genetics Single Gene NIPT (PreSeek)?

PreSeek is a non-invasive prenatal screening tool to assess fetal risk for some of the most common autosomal dominant disorders observed in pregnancy. Patients carrying a singleton pregnancy at 9 weeks gestation or greater are eligible for PreSeek. In addition, pregnancies conceived via egg and/or sperm donors and/or utilizing a surrogate gestation carrier are also eligible. Biological parental specimens, along with the gestational carrier, are required for analysis. While PreSeek can also be utilized to assess risk for a paternal variant in one of the genes assessed via the PreSeek panel, we are unable to provide an informative result for fetal status of a maternally-inherited variant at this time.  

 


Where can I find additional information on the cost of testing, CPT codes, verification of benefits, and patient assistance plans?

Cost of testing can be obtained from our billing (billing@baylorgenetics.com) and business development (businessdevelopment@baylorgenetics.com) teams; please include the test code of interest and institution or insurance provider. CPT codes are available for each test within our test menu. Additional billing information, including a portal to submit a Verification of Benefits Request, a list of insurance plans in-network with Baylor Geneticsour patient assistance program, and payment portal information, can be found here. 

 


 

I am looking to order a test but believe it has been discontinued. Where can I find information on discontinued tests?

A list of discontinued tests can be found here. Looking for a comparative alternative? Please reach out to our Customer Experience Specialists at 1.800.411.4363 or fill out our contact form. Please include the canceled test you are looking to compare and we would be happy to suggest an alternative. 

 


What is the minimum amount for testing?

Our minimum amount is dependent on the sample type and testing methodology, which can be found in our test catalog. To request exceptions for unvalidated sample types or minimal volumes, please contact us by calling 1.800.411.4363 or fill out our contact form.

 


Can I send extracted DNA?

In general, BG prefers to extract specimens here to maximize the likelihood of meeting our quality metrics. However, for certain methodologies, extracted DNA from a validated specimen type may be sent when the originating specimen is an appropriate sample type for a test.  The origin of the extracted DNA should be noted on the requisition. Please note Global Metabolomics, biochemical/enzymatic analyses, FISH analysis, and chromosome analysis cannot be performed on extracted DNA.

The following parameters must be met for extracted DNA for Sequence and NGS Analysis, Southern blots, Microarrays, and MLPA testing:

Extracted in a CLIA-certified laboratory

20 ug at 0.5 – 1.0 ug/ul concentration

260/280 ratio: between 1.75 and 2.00

260/230 ratio: greater than 1.70

 


How do I add on testing to an existing sample?

You can submit your request by completing and returning a Test Revision Authorization Form, including billing information.  BG will assess if adequate specimen remains and if so, the add-on testing will be initiated. If the adequate specimen does not remain, BG will issue a cancellation memo. Further information regarding test additions can be found here.

 


What is your cancellation policy?

A request for test cancellation will be honored if the request is made within 24 business hours of our laboratory receiving the sample. For more information about test cancellations , click here.

 


Can I speak to a Genetic Counselor?

Yes. Emailing help@baylorgenetics.com is our preferred method of contacting our GC team as this allows asynchronous communication and shared documentation. Our board-certified laboratory Genetic Counselors are available Monday – Friday, 8 am to 6 pm CST, to help answer any clinical questions or testing inquiries. These requests must be received from the ordering physician or a genetic professional. Urgent matters may be called to 1.800.411.4363 and our customer experience specialists will assist.

 


 

Where can I find the proper requisition for the test I want to order?

Find the appropriate test by test code or gene name by visiting our test catalog. The requisition can be found as a link under the desired test. In addition, a listing of our requisitions can also be found here.

 


 

Are you open to accepting specimen deliveries on Saturday?

Our laboratory is open to accept deliveries on Saturday, 8am – 5pm CST, provided the courier service is also operating that day. Please mark your package for Saturday delivery, if you would like your sample to arrive at our lab on a Saturday. Note, we are unable to accept deliveries on Sunday.

 


I am interested in having my patient’s exome testing re-analyzed. How do I make this request?

Whole Exome Sequencing (WES) reanalysis is available via test code 1900. Additional information such as turn-around time and release to new physicians may also be found at that link. Other analyses such as array do not currently offer reanalysis, however specific questions may be emailed to help@baylorgenetics.com.

 


 

I am interested in having my patient’s specific variant re-assessed. How do I make this request?

Requests for current variant classification or re-curation may be submitted through our contact form. Please include the patient’s name and date of birth, or Baylor Genetics Lab and Family numbers, along with gene(s) and variant(s) of interest. Please limit requests to no more than 5 variants and include any pertinent new information or publications you would like the lab to consider.

 


 

Do you provide raw data?

Yes. Please fill out the raw data form by clicking here to submit a raw data request.

 


How do I order a kit for my patients?

Visit our test kit supply page to order kits for testing. Contact us if you need assistance.

 


 

I have questions about my patient’s report.

Please call 1.800.411.4363 or fill out our contact form. Please include the patient’s name and date of birth, or Baylor Genetics Lab and Family numbers, along with how we can help address the specific issue(s).

 


Do you provide consent forms in other languages?

Yes, our consents are available in English, Arabic, French, and Spanish. Click here to access our consent forms page. BG will accept physician verification if consenting was done in a language other than English, Arabic, French, and Spanish.

Menu