Qin Sun
PhD
Sr. Division Director, Biochemical Genetics
Dr. Qin Sun serves as the Senior Division Director of Biochemical Genetics at Baylor Genetics. In addition to his role at BG, he is an Associate Professor in the Department of Molecular and Human Genetics as well as the Director of the Analyte Center at Baylor College of Medicine (BCM).
Dr. Sun graduated with his bachelor’s in microbiology from Shandong University in China. He continued his education at The University of Texas at Houston and graduated with his PhD in microbiology and molecular genetics. After graduation, he attended BCM as a fellow in the Department of Molecular and Human Genetics. Furthermore, he is board certified by the American Board of Medical Genetics in for Clinical Biochemical Genetics.
Position
Associate Professor
Molecular and Human Genetics
Baylor College of Medicine
Houston, TX, United States
Sr. Division Director
Biochemical Genetics
Baylor Genetics
Houston, TX, United States
Education
Fellowship at Baylor College of Medicine
Molecular and Human Genetics
Houston, TX, United States
PhD from University of Texas at Houston
Houston, TX, United States
Certifications
Clinical Biochemical Genetics
American Board of Medical Genetics
Publications
Opening a window on lysosomal acid lipase deficiency: Biochemical, molecular, and epidemiological insights
Gerarda Cappuccio, Taraka R. Donti, Leroy Hubert, Qin Sun, Sarah H. Elsea. Opening a window on lysosomal acid lipase deficiency: Biochemical, molecular, and epidemiological insights. J Inherit Metab Dis. Dec 2019; 42: 509– 518. PMID: 30684275
Clinical Metabolomics to Segregate Aromatic Amino Acid Decarboxylase Deficiency From Drug-Induced Metabolite Elevations
Pappan KL, Kennedy AD, Magoulas PL, Hanchard NA, Sun Q, Elsea SH. Clinical Metabolomics to Segregate Aromatic Amino Acid Decarboxylase Deficiency From Drug-Induced Metabolite Elevations. Pediatr Neurol. 2017 Oct;75:66-72. Epub 2017 Jun 29. PMID: 28823629
Elucidation of the complex metabolic profile of cerebrospinal fluid using an untargeted biochemical profiling assay
Kennedy AD, Pappan KL, Donti TR, Evans AM, Wulff JE, Miller LAD, Reid Sutton V, Sun Q, Miller MJ, Elsea SH. Elucidation of the complex metabolic profile of cerebrospinal fluid using an untargeted biochemical profiling assay. Mol Genet Metab. 2017 Apr 9. PMID: 28412083
Simultaneous determination of plasma total homocysteine and methionine by liquid chromatography-tandem mass spectrometry
Jiang Y, Mistretta B, Elsea S, Sun Q. Simultaneous determination of plasma total homocysteine and methionine by liquid chromatography-tandem mass spectrometry. Clin Chim Acta. 2017 Jan;464:93-97. PMID: 27845054
Chronic Oral L-Carnitine Supplementation Drives Marked Plasma TMAO Elevations in Patients with Organic Acidemias Despite Dietary Meat Restrictions
Miller MJ, Bostwick BL, Kennedy AD, Donti TR, Sun Q, Sutton VR, Elsea SH. Chronic Oral L-Carnitine Supplementation Drives Marked Plasma TMAO Elevations in Patients with Organic Acidemias Despite Dietary Meat Restrictions. JIMD Rep. 2016;30:39-44. PMID: 26936850
Metabolomic Profiling of Human Urine as a Screen for Multiple Inborn Errors of Metabolism
Kennedy AD, Miller MJ, Beebe K, Wulff JE, Evans AM, Miller LA, Sutton VR, Sun Q, Elsea SH. Metabolomic Profiling of Human Urine as a Screen for Multiple Inborn Errors of Metabolism. Genet Test Mol Biomarkers. 2016 Sep;20(9):485-95. PMID: 27448163
Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemia
Pankowicz FP, Barzi M, Legras X, Hubert L, Mi T, Tomolonis JA, Ravishankar M, Sun Q, Yang D, Borowiak M, Sumazin P, Elsea SH, Bissig-Choisat B, Bissig KD. Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemia. Nat Commun. 2016 Aug 30;7:12642. PMID: 27572891
Diagnosis of adenylosuccinate lyase deficiency by metabolomic profiling in plasma reveals a phenotypic spectrum
Donti TR, Cappuccio G, Hubert L, Neira J, Atwal PS, Miller MJ, Cardon AL, Sutton VR, Porter BE, Baumer FM, Wangler MF, Sun Q, Emrick LT, Elsea SH. Diagnosis of adenylosuccinate lyase deficiency by metabolomic profiling in plasma reveals a phenotypic spectrum. Mol Genet Metab Rep. 2016 Jul 27;8:61-6. PMID: 27504266
Elevations of C14:1 and C14:2 Plasma Acylcarnitines in Fasted Children: A Diagnostic Dilemma
Burrage LC, Miller MJ, Wong LJ, Kennedy AD, Sutton VR, Sun Q, Elsea SH, Graham BH. Elevations of C14:1 and C14:2 Plasma Acylcarnitines in Fasted Children: A Diagnostic Dilemma. J Pediatr. 2016 Feb;169:208-13.e2. PMID: 26602010
Urine Pyrimidine Metabolite Determination by HPLC Tandem Mass Spectrometry
Sun Q. Urine Pyrimidine Metabolite Determination by HPLC Tandem Mass Spectrometry. Methods Mol Biol. 1378:237-42. 2016. Springer. PMID 26602135
Urine Purine Metabolite Determination by UPLC Tandem Mass Spectrometry
Sun Q. Urine Purine Metabolite Determination by UPLC Tandem Mass Spectrometry. Methods Mol Biol. 1378:227-35. 2016. Springer. PMID: 26602134
Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency
Burrage LC, Sun Q, Elsea SH, Jiang MM, Nagamani SC, Frankel AE, Stone E, Alters SE, Johnson DE, Rowlinson SW, Georgiou G; Members of Urea Cycle Disorders Consortium, Lee BH. Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency. Hum Mol Genet. 2015 Nov 15;24(22):6417-27. PMID: 26358771
Recurrent ACADVL molecular findings in individuals with a positive newborn screen for very long chain acyl-coA dehydrogenase (VLCAD) deficiency in the United States
Miller MJ, Burrage LC, Gibson JB, Strenk ME, Lose EJ, Bick DP, Elsea SH, Sutton VR, Sun Q, Graham BH, Craigen WJ, Zhang VW, Wong LJ. Recurrent ACADVL molecular findings in individuals with a positive newborn screen for very long chain acyl-coA dehydrogenase (VLCAD) deficiency in the United States. Mol Genet Metab. 2015 Nov;116(3):139-45. PMID: 26385305
Untargeted metabolomic analysis for the clinical screening of inborn errors of metabolism
Miller MJ, Kennedy AD, Eckhart AD, Burrage LC, Wulff JE, Miller LA, Milburn MV, Ryals JA, Beaudet AL, Sun Q, Sutton VR, Elsea SH. Untargeted metabolomic analysis for the clinical screening of inborn errors of metabolism. J Inherit Metab Dis. 2015 Nov;38(6):1029-39. PMID: 25875217
Corrigendum to “Improvement of regressive autism symptoms in a child with TMLHE deficiency following carnitine supplementation”
Ziats MN, Comeaux MS, Yang Y, Scaglia F, Elsea SH, Sun Q, Beaudet AL, Schaaf CP. Corrigendum to “Improvement of regressive autism symptoms in a child with TMLHE deficiency following carnitine supplementation.” Am J Med Genet A. 2015 Oct;167A(10):2496. PMID: 26355286
Corrigendum to "Improvement of regressive autism symptoms in a child with TMLHE deficiency following carnitine supplementation"
Ziats MN, Comeaux MS, Yang Y, Scaglia F, Elsea SH, Sun Q, Beaudet AL, Schaaf CP. Corrigendum to “Improvement of regressive autism symptoms in a child with TMLHE deficiency following carnitine supplementation.” Am J Med Genet A. 2015 Oct;167A(10):2496. PMID: 26355286
Improvement of regressive autism symptoms in a child with TMLHE deficiency following carnitine supplementation
Ziats MN, Comeaux MS, Yang Y, Scaglia F, Elsea SH, Sun Q, Beaudet AL, Schaaf CP. Improvement of regressive autism symptoms in a child with TMLHE deficiency following carnitine supplementation. Am J Med Genet A. 2015 Sep;167A(9):2162-7. PMID: 25943046
Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis
Rabinovich S, Adler L, Yizhak K, Sarver A, Silberman A, Agron S, Stettner N, Sun Q, Brandis A, Helbling D, Korman S, Itzkovitz S, Dimmock D, Ulitsky I, Nagamani SC, Ruppin E, Erez A. 2015. Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis. Nature. 2015. 527(7578):379-83. PMID: 26560030
Aromatic L-amino acid decarboxylase deficiency diagnosed by clinical metabolomic profiling of plasma
Atwal PS, Donti TR, Cardon AL, Bacino CA, Sun Q, Emrick L, Reid Sutton V, Elsea SH. Aromatic L-amino acid decarboxylase deficiency diagnosed by clinical metabolomic profiling of plasma. Mol Genet Metab. 2015 Jun-Jul;115(2-3):91-4. PMID: 25956449
Qin Sun
PhD
Sr. Division Director, Biochemical Genetics
Dr. Qin Sun serves as the Senior Division Director of Biochemical Genetics at Baylor Genetics. In addition to his role at BG, he is an Associate Professor in the Department of Molecular and Human Genetics as well as the Director of the Analyte Center at Baylor College of Medicine (BCM).
Dr. Sun graduated with his bachelor’s in microbiology from Shandong University in China. He continued his education at The University of Texas at Houston and graduated with his PhD in microbiology and molecular genetics. After graduation, he attended BCM as a fellow in the Department of Molecular and Human Genetics. Furthermore, he is board certified by the American Board of Medical Genetics in for Clinical Biochemical Genetics.
Position
Associate Professor
Molecular and Human Genetics
Baylor College of Medicine
Houston, TX, United States
Sr. Division Director
Biochemical Genetics
Baylor Genetics
Houston, TX, United States
Education
Fellowship at Baylor College of Medicine
Molecular and Human Genetics
Houston, TX, United States
PhD from University of Texas at Houston
Houston, TX, United States
Certifications
Clinical Biochemical Genetics
American Board of Medical Genetics
Publications
Opening a window on lysosomal acid lipase deficiency: Biochemical, molecular, and epidemiological insights
Gerarda Cappuccio, Taraka R. Donti, Leroy Hubert, Qin Sun, Sarah H. Elsea. Opening a window on lysosomal acid lipase deficiency: Biochemical, molecular, and epidemiological insights. J Inherit Metab Dis. Dec 2019; 42: 509– 518. PMID: 30684275
Clinical Metabolomics to Segregate Aromatic Amino Acid Decarboxylase Deficiency From Drug-Induced Metabolite Elevations
Pappan KL, Kennedy AD, Magoulas PL, Hanchard NA, Sun Q, Elsea SH. Clinical Metabolomics to Segregate Aromatic Amino Acid Decarboxylase Deficiency From Drug-Induced Metabolite Elevations. Pediatr Neurol. 2017 Oct;75:66-72. Epub 2017 Jun 29. PMID: 28823629
Elucidation of the complex metabolic profile of cerebrospinal fluid using an untargeted biochemical profiling assay
Kennedy AD, Pappan KL, Donti TR, Evans AM, Wulff JE, Miller LAD, Reid Sutton V, Sun Q, Miller MJ, Elsea SH. Elucidation of the complex metabolic profile of cerebrospinal fluid using an untargeted biochemical profiling assay. Mol Genet Metab. 2017 Apr 9. PMID: 28412083
Simultaneous determination of plasma total homocysteine and methionine by liquid chromatography-tandem mass spectrometry
Jiang Y, Mistretta B, Elsea S, Sun Q. Simultaneous determination of plasma total homocysteine and methionine by liquid chromatography-tandem mass spectrometry. Clin Chim Acta. 2017 Jan;464:93-97. PMID: 27845054
Chronic Oral L-Carnitine Supplementation Drives Marked Plasma TMAO Elevations in Patients with Organic Acidemias Despite Dietary Meat Restrictions
Miller MJ, Bostwick BL, Kennedy AD, Donti TR, Sun Q, Sutton VR, Elsea SH. Chronic Oral L-Carnitine Supplementation Drives Marked Plasma TMAO Elevations in Patients with Organic Acidemias Despite Dietary Meat Restrictions. JIMD Rep. 2016;30:39-44. PMID: 26936850
Metabolomic Profiling of Human Urine as a Screen for Multiple Inborn Errors of Metabolism
Kennedy AD, Miller MJ, Beebe K, Wulff JE, Evans AM, Miller LA, Sutton VR, Sun Q, Elsea SH. Metabolomic Profiling of Human Urine as a Screen for Multiple Inborn Errors of Metabolism. Genet Test Mol Biomarkers. 2016 Sep;20(9):485-95. PMID: 27448163
Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemia
Pankowicz FP, Barzi M, Legras X, Hubert L, Mi T, Tomolonis JA, Ravishankar M, Sun Q, Yang D, Borowiak M, Sumazin P, Elsea SH, Bissig-Choisat B, Bissig KD. Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemia. Nat Commun. 2016 Aug 30;7:12642. PMID: 27572891
Diagnosis of adenylosuccinate lyase deficiency by metabolomic profiling in plasma reveals a phenotypic spectrum
Donti TR, Cappuccio G, Hubert L, Neira J, Atwal PS, Miller MJ, Cardon AL, Sutton VR, Porter BE, Baumer FM, Wangler MF, Sun Q, Emrick LT, Elsea SH. Diagnosis of adenylosuccinate lyase deficiency by metabolomic profiling in plasma reveals a phenotypic spectrum. Mol Genet Metab Rep. 2016 Jul 27;8:61-6. PMID: 27504266
Elevations of C14:1 and C14:2 Plasma Acylcarnitines in Fasted Children: A Diagnostic Dilemma
Burrage LC, Miller MJ, Wong LJ, Kennedy AD, Sutton VR, Sun Q, Elsea SH, Graham BH. Elevations of C14:1 and C14:2 Plasma Acylcarnitines in Fasted Children: A Diagnostic Dilemma. J Pediatr. 2016 Feb;169:208-13.e2. PMID: 26602010
Urine Pyrimidine Metabolite Determination by HPLC Tandem Mass Spectrometry
Sun Q. Urine Pyrimidine Metabolite Determination by HPLC Tandem Mass Spectrometry. Methods Mol Biol. 1378:237-42. 2016. Springer. PMID 26602135
Urine Purine Metabolite Determination by UPLC Tandem Mass Spectrometry
Sun Q. Urine Purine Metabolite Determination by UPLC Tandem Mass Spectrometry. Methods Mol Biol. 1378:227-35. 2016. Springer. PMID: 26602134
Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency
Burrage LC, Sun Q, Elsea SH, Jiang MM, Nagamani SC, Frankel AE, Stone E, Alters SE, Johnson DE, Rowlinson SW, Georgiou G; Members of Urea Cycle Disorders Consortium, Lee BH. Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency. Hum Mol Genet. 2015 Nov 15;24(22):6417-27. PMID: 26358771
Recurrent ACADVL molecular findings in individuals with a positive newborn screen for very long chain acyl-coA dehydrogenase (VLCAD) deficiency in the United States
Miller MJ, Burrage LC, Gibson JB, Strenk ME, Lose EJ, Bick DP, Elsea SH, Sutton VR, Sun Q, Graham BH, Craigen WJ, Zhang VW, Wong LJ. Recurrent ACADVL molecular findings in individuals with a positive newborn screen for very long chain acyl-coA dehydrogenase (VLCAD) deficiency in the United States. Mol Genet Metab. 2015 Nov;116(3):139-45. PMID: 26385305
Untargeted metabolomic analysis for the clinical screening of inborn errors of metabolism
Miller MJ, Kennedy AD, Eckhart AD, Burrage LC, Wulff JE, Miller LA, Milburn MV, Ryals JA, Beaudet AL, Sun Q, Sutton VR, Elsea SH. Untargeted metabolomic analysis for the clinical screening of inborn errors of metabolism. J Inherit Metab Dis. 2015 Nov;38(6):1029-39. PMID: 25875217
Corrigendum to “Improvement of regressive autism symptoms in a child with TMLHE deficiency following carnitine supplementation”
Ziats MN, Comeaux MS, Yang Y, Scaglia F, Elsea SH, Sun Q, Beaudet AL, Schaaf CP. Corrigendum to “Improvement of regressive autism symptoms in a child with TMLHE deficiency following carnitine supplementation.” Am J Med Genet A. 2015 Oct;167A(10):2496. PMID: 26355286
Corrigendum to "Improvement of regressive autism symptoms in a child with TMLHE deficiency following carnitine supplementation"
Ziats MN, Comeaux MS, Yang Y, Scaglia F, Elsea SH, Sun Q, Beaudet AL, Schaaf CP. Corrigendum to “Improvement of regressive autism symptoms in a child with TMLHE deficiency following carnitine supplementation.” Am J Med Genet A. 2015 Oct;167A(10):2496. PMID: 26355286
Improvement of regressive autism symptoms in a child with TMLHE deficiency following carnitine supplementation
Ziats MN, Comeaux MS, Yang Y, Scaglia F, Elsea SH, Sun Q, Beaudet AL, Schaaf CP. Improvement of regressive autism symptoms in a child with TMLHE deficiency following carnitine supplementation. Am J Med Genet A. 2015 Sep;167A(9):2162-7. PMID: 25943046
Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis
Rabinovich S, Adler L, Yizhak K, Sarver A, Silberman A, Agron S, Stettner N, Sun Q, Brandis A, Helbling D, Korman S, Itzkovitz S, Dimmock D, Ulitsky I, Nagamani SC, Ruppin E, Erez A. 2015. Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis. Nature. 2015. 527(7578):379-83. PMID: 26560030
Aromatic L-amino acid decarboxylase deficiency diagnosed by clinical metabolomic profiling of plasma
Atwal PS, Donti TR, Cardon AL, Bacino CA, Sun Q, Emrick L, Reid Sutton V, Elsea SH. Aromatic L-amino acid decarboxylase deficiency diagnosed by clinical metabolomic profiling of plasma. Mol Genet Metab. 2015 Jun-Jul;115(2-3):91-4. PMID: 25956449