Ning Liu
PhD
Assistant Clinical Director, Biochemical Genetics
Dr. Ning Liu is the Assistant Clinical Director of Biochemical Genetics at Baylor Genetics. In addition to her role at Baylor Genetics, she is an Assistant Professor in the Department of Molecular and Human Genetics at Baylor College of Medicine (BCM), specializing in the implementation of clinical metabolomics for metabolic disease screening. Her research focuses on the discovery of novel disease-causing genes and variants, identification of novel biomarkers, and developing new diagnostic technologies for early diagnosis of metabolic disorders.
Dr. Liu graduated with her bachelor’s in biotechnology from Northeast Normal University in Changchun, China. She continued her studies at the University of Rochester in Rochester, NY, with a focus on chromatin remodeling and graduated with her PhD in biochemistry.
After graduation, Dr. Liu moved to Houston and completed her postdoctoral fellowship at BCM in Dr. Hugo J. Bellen’s Lab, where she was part of the Undiagnosed Diseases Network team. Upon completion, she joined the American Board of Medical Genetics and Genomics Clinical Biochemical Genetics Fellowship program at BCM.
Position
Assistant Professor
Molecular and Human Genetics
Baylor College of Medicine
Houston, TX, United States
Assistant Clinical Director
Biochemical Genetics
Baylor Genetics
Houston, TX, United States
Education
Postdoctoral Fellowship at Baylor College of Medicine
Houston, TX, United States
PhD from University of Rochester
Rochester, NY, United States
BS from Northeast Normal University
Changchun, Jilin, China
Certifications
Clinical Biochemical Genetics
American Board of Medical Genetics
Publications
Hematologic presentation and the role of untargeted metabolomics analysis in monitoring treatment for riboflavin transporter deficiency
Pillai NR, Amin H, Gijavanekar C, Liu N, et al. Hematologic presentation and the role of untargeted metabolomics analysis in monitoring treatment for riboflavin transporter deficiency. Am J Med Genet Al. 2020; doi: 10.1002/ajmg.a.61851. PMID: 32909658
Integrated analysis of metabolomic profiling and exome data supplements sequence variant interpretation, classification, and diagnosis
Alaimo JT, Glinton KE, Liu N, Xiao J, Yang Y, Reid Sutton V, Elsea SH. Integrated analysis of metabolomic profiling and exome data supplements sequence variant interpretation, classification, and diagnosis. Genet Med. 2020 Sep;22(9):1560-1566. PMID: 32439973
Functional variants in TBX2 are associated with a syndromic cardiovascular and skeletal developmental disorder
Liu N, Schoch K, Luo X, et al. Functional variants in TBX2 are associated with a syndromic cardiovascular and skeletal developmental disorder. Hum Mol Genet. 2018;27(14):2454-2465. PMID: 29726930
Preparation of nucleosomes containing a specific H2A-H2A cross-link forming a DNA-constraining loop structure
Liu N, Hayes JJ. Preparation of nucleosomes containing a specific H2A-H2A cross-link forming a DNA-constraining loop structure. Methods Mol Biol. 2012;833:351-371. PMID: 22183604
SWI/SNF- and RSC-Catalyzed Nucleosome Mobilization Requires Internal DNA Loop Translocation within Nucleosomes
Liu N, Peterson CL, Hayes JJ. SWI/SNF- and RSC-catalyzed nucleosome mobilization requires internal DNA loop translocation within nucleosomes. Mol Cell Biol. 2011;31(20):4165-4175. PMID: 21859889
Mechanism(s) of SWI/SNF-induced nucleosome mobilization
Liu N, Balliano A, Hayes JJ. Mechanism(s) of SWI/SNF-induced nucleosome mobilization. Chembiochem. 2011;12(2):196-204. PMID: 21243709
When push comes to shove: SWI/SNF uses a nucleosome to get rid of a nucleosome
Liu N, Hayes JJ. When push comes to shove: SWI/SNF uses a nucleosome to get rid of a nucleosome. Mol Cell. 2010;38(4):484-486. PMID: 20513424
Ning Liu
PhD
Assistant Clinical Director, Biochemical Genetics
Dr. Ning Liu is the Assistant Clinical Director of Biochemical Genetics at Baylor Genetics. In addition to her role at Baylor Genetics, she is an Assistant Professor in the Department of Molecular and Human Genetics at Baylor College of Medicine (BCM), specializing in the implementation of clinical metabolomics for metabolic disease screening. Her research focuses on the discovery of novel disease-causing genes and variants, identification of novel biomarkers, and developing new diagnostic technologies for early diagnosis of metabolic disorders.
Dr. Liu graduated with her bachelor’s in biotechnology from Northeast Normal University in Changchun, China. She continued her studies at the University of Rochester in Rochester, NY, with a focus on chromatin remodeling and graduated with her PhD in biochemistry.
After graduation, Dr. Liu moved to Houston and completed her postdoctoral fellowship at BCM in Dr. Hugo J. Bellen’s Lab, where she was part of the Undiagnosed Diseases Network team. Upon completion, she joined the American Board of Medical Genetics and Genomics Clinical Biochemical Genetics Fellowship program at BCM.
Position
Assistant Professor
Molecular and Human Genetics
Baylor College of Medicine
Houston, TX, United States
Assistant Clinical Director
Biochemical Genetics
Baylor Genetics
Houston, TX, United States
Education
Postdoctoral Fellowship at Baylor College of Medicine
Houston, TX, United States
PhD from University of Rochester
Rochester, NY, United States
BS from Northeast Normal University
Changchun, Jilin, China
Certifications
Clinical Biochemical Genetics
American Board of Medical Genetics
Publications
Hematologic presentation and the role of untargeted metabolomics analysis in monitoring treatment for riboflavin transporter deficiency
Pillai NR, Amin H, Gijavanekar C, Liu N, et al. Hematologic presentation and the role of untargeted metabolomics analysis in monitoring treatment for riboflavin transporter deficiency. Am J Med Genet Al. 2020; doi: 10.1002/ajmg.a.61851. PMID: 32909658
Integrated analysis of metabolomic profiling and exome data supplements sequence variant interpretation, classification, and diagnosis
Alaimo JT, Glinton KE, Liu N, Xiao J, Yang Y, Reid Sutton V, Elsea SH. Integrated analysis of metabolomic profiling and exome data supplements sequence variant interpretation, classification, and diagnosis. Genet Med. 2020 Sep;22(9):1560-1566. PMID: 32439973
Functional variants in TBX2 are associated with a syndromic cardiovascular and skeletal developmental disorder
Liu N, Schoch K, Luo X, et al. Functional variants in TBX2 are associated with a syndromic cardiovascular and skeletal developmental disorder. Hum Mol Genet. 2018;27(14):2454-2465. PMID: 29726930
Preparation of nucleosomes containing a specific H2A-H2A cross-link forming a DNA-constraining loop structure
Liu N, Hayes JJ. Preparation of nucleosomes containing a specific H2A-H2A cross-link forming a DNA-constraining loop structure. Methods Mol Biol. 2012;833:351-371. PMID: 22183604
SWI/SNF- and RSC-Catalyzed Nucleosome Mobilization Requires Internal DNA Loop Translocation within Nucleosomes
Liu N, Peterson CL, Hayes JJ. SWI/SNF- and RSC-catalyzed nucleosome mobilization requires internal DNA loop translocation within nucleosomes. Mol Cell Biol. 2011;31(20):4165-4175. PMID: 21859889
Mechanism(s) of SWI/SNF-induced nucleosome mobilization
Liu N, Balliano A, Hayes JJ. Mechanism(s) of SWI/SNF-induced nucleosome mobilization. Chembiochem. 2011;12(2):196-204. PMID: 21243709
When push comes to shove: SWI/SNF uses a nucleosome to get rid of a nucleosome
Liu N, Hayes JJ. When push comes to shove: SWI/SNF uses a nucleosome to get rid of a nucleosome. Mol Cell. 2010;38(4):484-486. PMID: 20513424