Dear Valued Clients,
Effective December 16, 2019, in a continuing effort to optimize our offerings, Baylor Genetics has updated four FISH panels and will begin offering three new FISH panels. The changes to the probes used in each FISH panel are based on the latest recommendations from the World Health Organization.
The FISH probes for the following Oncology FISH test codes have been updated:
Test Code |
Test Description |
Current FISH Panel |
New FISH Panel |
8010 |
Acute Lymphoblastic Leukemia Panel |
MYB CDKN2A BCR/ABL KMT2A ETV6/RUNX1 IGH |
CDKN2A BCR/ABL KMT2A IGH CEP 4 CEP 10 |
8015 |
Multiple Myeloma Panel |
CEP 9 RB1 P53 IGH SNRPN |
CKS1B/CDKN2C D7S486 CEP 9 RB1 P53 IGH SNRPN |
8020 |
Non-Hodgkin Lymphoma Panel |
BCL6 ALK ATM IGH P53 |
BCL6 IGH/CCND1 MYC MALT1 BCL2 |
8040 |
Chronic Lymphocytic Leukemia Panel |
CEP 12 ATM/p53 MYB D13S319 IGH |
CEP 12 ATM/p53 MYB D13S319 IGH IGH/CCND1 |
In order to update our Oncology FISH catalog, we will be offering the following new tests:
Test Code |
Test Description |
New FISH Panel |
8790 |
Multiple Myeloma IgH Rearrangement Panel |
IGH/FGFR3 IGH/MAF IGH/CCND1 |
8791 |
Eosinophilia Panel |
PDGFRB FGFR1 JAK2 PDGFRA/CJIC2/FIP1L1 CBFB |
8792 |
ALL Pediatric Panel |
BCR/ABL KMT2A ETV6/RUNX1 CEP 4 CEP 10 TCF3/PBX1 |
In addition, for myeloma samples we will begin offering Plasma Cell Enrichment in order to enhance our detection of cytogenetic abnormalities by FISH in patients with Plasma cell Neoplasms.
If you have specific questions regarding these updates, please contact your Baylor Genetics account representative or feel free to call our Client Relations Division at 1.800.411.4363.
Thank you for your continued business.
